What protocol is the Dou Proxy proxying? LDAP or RADIUS?
If RADIUS - this should work:
https://community.fortinet.com/t5/FortiGate/Technical-Tip-IKEv2-Dialup-IPsec-tunnel-with-RADIUS-and/... - DUO being a proxy should basically only mean that your server on FortiGate would be DUO and on DOU the target would be NPS. After authentication success against NPS, DOU would ask for a second factor. Once answered, DUO would respond to FortiGate as the RADIUS server.
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