Virtual IPs stop ping and HTTP traffic

Hello community 

Using a configuration that takes WAN1 port forwards to a specific IP address on LAN using virtual IPs. With this enabled the particular IP address on LAN can no longer ping out or make HTTP requests. If the IP address of that computer is changed to any other address on the subnet the ping out then works and HTTP requests restored. 

How then can I get the computer with virtual IP address associated with it to accept all the traffic? Maybe my lack of understanding how virtual IPs work as well.

Appreciate it